Buffalo Cauliflower Grilled Cheese

Featured in: Weeknight Dinners

This dish combines spicy roasted buffalo cauliflower florets with a creamy ranch spread and melted sharp cheddar and mozzarella cheeses. The mixture is layered between slices of sourdough bread, buttered and grilled until golden and crispy. Roasting the cauliflower with garlic, smoked paprika, and buffalo sauce creates a flavorful, tender filling. The sandwich offers a perfect balance of heat, creaminess, and crunch, making it a satisfying and easy-to-make main dish for a vegetarian option.

Updated on Fri, 28 Nov 2025 14:39:00 GMT
Buffalo Cauliflower Ranch Grilled Cheese with melted cheese oozing between golden crusty bread. Pin
Buffalo Cauliflower Ranch Grilled Cheese with melted cheese oozing between golden crusty bread. | grillandbites.com

A bold, flavorful twist on classic grilled cheese: spicy roasted cauliflower, creamy ranch, and gooey melted cheese between crispy golden bread slices.

This grilled cheese became an instant favorite the first time I made it, impressing everyone at the table with its unique blend of flavors.

Ingredients

  • For the Buffalo Cauliflower: 3 cups small cauliflower florets, 2 tablespoons olive oil, 1/2 teaspoon garlic powder, 1/2 teaspoon smoked paprika, 1/4 teaspoon salt, 1/4 teaspoon black pepper, 1/3 cup buffalo wing sauce
  • For the Ranch Spread: 1/2 cup ranch dressing (store-bought or homemade), 1 tablespoon chopped fresh chives (optional), 1 tablespoon chopped fresh dill (optional)
  • For the Sandwiches: 8 slices sourdough or country-style bread, 2 cups shredded sharp cheddar cheese, 1 cup shredded mozzarella cheese, 2 tablespoons unsalted butter softened

Instructions

Preheat Oven:
Preheat oven to 425°F (220°C) and line a baking sheet with parchment paper.
Prepare Cauliflower:
Toss cauliflower florets with olive oil, garlic powder, smoked paprika, salt, and black pepper. Spread on the baking sheet.
Roast Cauliflower:
Roast for 15 minutes stirring halfway through. Toss with buffalo wing sauce and roast 5 more minutes. Set aside.
Make Ranch Spread:
Mix ranch dressing with chives and dill if using.
Assemble Sandwiches:
Spread ranch mixture on one side of bread slices. On four slices sprinkle half cheddar and mozzarella. Top with buffalo cauliflower and remaining cheese. Cover with remaining bread slices ranch-side down.
Prepare to Grill:
Heat skillet or griddle over medium heat. Spread butter on outer sides of sandwiches.
Grill Sandwiches:
Grill 3 to 4 minutes per side pressing gently until bread is golden and cheese melted.
Serve:
Cool for 1 minute, slice, and serve warm.
Spicy roasted Buffalo Cauliflower, cheddar, and mozzarella make this a flavorful grilled cheese. Pin
Spicy roasted Buffalo Cauliflower, cheddar, and mozzarella make this a flavorful grilled cheese. | grillandbites.com

This recipe has brought my family closer as we've enjoyed sharing this flavorful sandwich together on cozy evenings.

Tips for Serving

Pair this grilled cheese with a crisp lager or a citrusy IPA to balance the spicy and creamy flavors.

Storage

Store leftover sandwiches in an airtight container in the refrigerator for up to 2 days. Reheat in a skillet for best texture.

Variations

Add sliced green onions or baby spinach for a fresh twist or drizzle extra buffalo sauce for more heat.

Imagine the crispy, cheesy Buffalo Cauliflower Ranch Grilled Cheese, perfect with a cold beer! Pin
Imagine the crispy, cheesy Buffalo Cauliflower Ranch Grilled Cheese, perfect with a cold beer! | grillandbites.com

This sandwich delivers exciting flavors with each bite, perfect for elevating your grilled cheese game.

Recipe FAQ

How do you prepare the buffalo cauliflower?

Cauliflower florets are tossed with olive oil, garlic powder, smoked paprika, salt, and pepper, then roasted. After initial roasting, they’re coated with buffalo wing sauce and roasted a bit longer for fullness of flavor.

Can I make the ranch spread from scratch?

Yes, you can mix mayonnaise, sour cream, herbs like dill and chives, and seasonings to create a fresh homemade ranch spread as an alternative to store-bought.

What breads work best for grilling?

Sourdough or country-style breads are ideal for their sturdy texture and ability to crisp evenly, providing a satisfying crunch.

How do I get the cheese melted perfectly?

Grill the sandwich over medium heat for 3–4 minutes per side, pressing gently to ensure even melting without burning the bread.

What can I add for an extra flavor boost?

Try drizzling extra buffalo sauce before serving or adding sliced green onions or baby spinach for freshness and texture variety.

Buffalo Cauliflower Grilled Cheese

Spicy roasted cauliflower and creamy ranch meld with melted cheese in a crispy grilled sandwich.

Prep duration
15 min
Cook duration
20 min
Overall duration
35 min


Skill level Easy

Heritage American

Output 4 Portions

Dietary requirements Vegetarian

Components

Buffalo Cauliflower

01 3 cups small cauliflower florets
02 2 tablespoons olive oil
03 1/2 teaspoon garlic powder
04 1/2 teaspoon smoked paprika
05 1/4 teaspoon salt
06 1/4 teaspoon black pepper
07 1/3 cup buffalo wing sauce

Ranch Spread

01 1/2 cup ranch dressing
02 1 tablespoon chopped fresh chives (optional)
03 1 tablespoon chopped fresh dill (optional)

Sandwiches

01 8 slices sourdough or country-style bread
02 2 cups shredded sharp cheddar cheese
03 1 cup shredded mozzarella cheese
04 2 tablespoons unsalted butter, softened

Directions

Phase 01

Preheat Oven and Prepare Baking Sheet: Preheat the oven to 425°F and line a baking sheet with parchment paper.

Phase 02

Season and Roast Cauliflower: In a bowl, combine cauliflower florets with olive oil, garlic powder, smoked paprika, salt, and black pepper. Spread evenly on the prepared baking sheet.

Phase 03

First Roast of Cauliflower: Roast the cauliflower for 15 minutes, stirring halfway through to ensure even cooking.

Phase 04

Add Buffalo Sauce and Final Roast: Remove cauliflower from the oven, toss with buffalo wing sauce, and return to roast for an additional 5 minutes. Set aside.

Phase 05

Prepare Ranch Mixture: In a small bowl, mix ranch dressing with chopped chives and dill if using.

Phase 06

Assemble Sandwiches: Lay out bread slices and spread the ranch mixture on one side of each slice. On four slices, layer half the cheddar and mozzarella cheeses, then top with buffalo cauliflower, followed by the remaining cheese. Cover with remaining bread slices, ranch side down.

Phase 07

Butter the Sandwiches: Heat a large skillet or griddle over medium heat. Spread softened butter on the outer sides of each sandwich.

Phase 08

Grill Sandwiches: Grill sandwiches for 3 to 4 minutes per side, pressing gently, until bread is golden brown and cheese is melted.

Phase 09

Rest and Serve: Allow sandwiches to cool for 1 minute, then slice and serve warm.

Tools needed

  • Baking sheet
  • Mixing bowls
  • Skillet or griddle
  • Spatula
  • Knife and cutting board

Allergy details

Review each ingredient for potential allergens and consult healthcare providers if you're uncertain about any components.
  • Contains wheat (bread), milk (cheese, butter, ranch).
  • Ranch dressing may contain eggs or soy; check labels if sensitive.
  • Use gluten-free bread for gluten-free option.
  • Use plant-based cheese, butter, and ranch for vegan adaptation.

Nutrition breakdown (per portion)

These values are estimates only and shouldn't replace professional medical guidance.
  • Energy: 430
  • Fat: 27 g
  • Carbohydrates: 35 g
  • Protein: 13 g